Mouse Skin Tissue - 63x
Shown above is a reconstruction of mouse skin thick tissue sections that were stained with Alexa Fluor 350 (wheat germ agglutinin; lectins), Alexa Fluor 568 (phalloidin; actin), and SYTOX Green (nuclei). In 2009, further advancing work with induced pluripotent stem cells (iPSCs), two Chinese research teams reportedly developed mice from mouse skin cells reprogrammed with retroviruses to act like embryonic stem cells. To produce the mice, scientists fused two early-stage mouse embryos, introduced the reprogrammed mouse skin cells into the resulting embryo, and then inserted it into a surrogate mouse. A first generation of mice displaying some abnormalities was produced, followed by a second generation that did not display similar abnormal characteristics.