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mCherry Fused to Vinculin

mCherry Fused to Human Vinculin

The protein vinculin is associated with focal adhesions and adherens junctions, which are complexes that act as nucleation sites for F-actin and as crosslinkers between the external medium, plasma membrane, and cytoskeleton. Research shows that by alternating between an active and inactive form, vinculin can regulate the mobility of cells. The specimen in the digital image presented above was part of a culture fluorescently labeled with EYFP fused to human vinculin. mCherry is one of the brightest and most commonly utilized red fluorescent proteins. The peak excitation and emission wavelengths of mCherry are 587 and 610 nanometers, respectively.