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LSM 700 Digital Image Gallery

Mouse Kidney Tissue

In the digital image presented above is a three-dimensional reconstruction of a 30-micrometer section of mouse kidney tissue that was stained with Alexa Fluor 350 (wheat germ agglutinin; highlighting lectins), Alexa Fluor 568 (phalloidin; labeling actin filaments), and SYTOX Green (nuclei). The kidneys are bilateral organs that play a critical homeostatic role in the regulation of body fluid composition and volume, and elimination of waste products. In a 1994 study by J M Pearson et al at the Department of Pathological Sciences, University Hospital of South Manchester, it was found that microscopy had an important diagnostic role in 75 percent of renal disease cases and was essential or necessary for diagnosis in 25 percent.