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LSM 700 Digital Image Gallery

Rat Kidney Tissue

Depicted in this section is a digital image of a three-dimensional reconstruction of rat kidney tissue stained with Alexa Fluor 488 (wheat germ agglutinin; highlighting lectins), Alexa Fluor 568 (phalloidin; labeling actin filaments), and DAPI (nuclei). In effort to accumulate more information on the rare kidney cancer called Wilms' tumor or nephroblastoma, erythropoietin (EPO) levels have been analyzed in rats with a Wilms' transplantable tumor. The diminished response pattern of EPO, a hormone produced by the kidney that promotes red blood cell formation in the bone marrow, was found to be similar in the rat models as to what has been observed in man.