Heilemann, M., van de Linde, S., Schuettpelz, M., Kasper, R., Seefeldt, B., Mukherjee, A., Tinnefeld, P. and Sauer, M.
Subdiffraction-resolution fluorescence imaging with conventional fluorescent probes. Angewandte Chemie International Edition 47: 6172-6176 (2008).

dSTORM uses conventional photoswitchable fluorescent dyes that can be reversibly cycled between a fluorescent and a dark state by irradiation with light of different wavelengths (see picture). This elegant approach can visualize cellular structures with a resolution of approximately 20 nm, far beyond the diffraction limit of light, without the need of an activator molecule.