Hinchcliffe, E. H.
Using long-term time-lapse imaging of mammalian cell cycle progression for laboratory instruction and analysis. Cell Biology Education 4: 284-290 (2005).

Cinemicrography - the capture of moving cellular sequences through the microscope - has been influential in revealing the dynamic nature of cellular behavior. Initially, cinemicrographic imaging was done using silver halide-based film, and these movies were instrumental in demonstrating the dramatic behavior of cell motility. Over the last 25 years, cell biology has benefited from improvements in electronic imaging technologies that have largely replaced silver-based film recordings. During the 1980s the use of analog video technology greatly expanded the use of light microscopy as an analytic tool. Over the last several years, the use of analog video-capture systems has been largely replaced by computer-based digital image-capture systems. With their high quantum efficiency, low-noise characteristics, and ease of use, imaging systems for digital micrography have revolutionized the study of the dynamic events of cell biology.