Vogelsang, J., Kasper, R., Steinhauer, C. Person, B., Heilemann, M., Sauer, M. and Tinnefeld, P.
A reducing and oxidizing system minimizes photobleaching and blinking of fluorescent dyes. Angewandte Chemie International Edition 47: 5465-5469 (2008).

On the ROXS: Photobleaching represents one of the main limitations of modern fluorescence microscopy. A reducing and oxidizing system (ROXS) has been introduced that recovers triplet states as well as charge-separated states through electron-transfer reactions (see picture). Thus the blinking and photobleaching of fluorophores is strikingly reduced.