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Imaging Neuromuscular Synapses

Dr. Hermann Aberle

University of Münster (Germany), Institute for Neurobiology

A single nerve branch exits a major motor nerve to innervate a muscle fiber in the lateral body wall region of a Drosophila larva. Immunohistochemical staining using antibodies against the cytoskeletal protein Futsch (green, Alexa Fluor 488) and the Drosophila vesicular glutamate transporter DVGLUT (red, Cy3).

Research Focus & Application:

The research focus of my lab is the establishment and remodeling of synaptic connections between motor neurons and muscle fibers.

Microscopy and Imaging Methods:

We use a ZEISS LSM 510 Meta because of its ability to image multiple colors at high resolution.